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Speech Essentials Improved

Speech Essentials Improved

Regular price $100.00
Regular price $100.00 Sale price
SAVE Liquid error (snippets/price line 119): Computation results in '-Infinity'% Sold out

Speech Essentials Improved: the foundational formula.

  • Supports speech and communication development*
  • Supports focus, attention and learning*
  • Supports healthy energy and stamina*
  • Supports calm and emotional balance*
  • Supports healthy nerve function and methylation*
  • The complete activated-B foundation: folinic acid + B2 + B6 + dual B12, no synthetic folic acid

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Speech Essentials Improved

Speech Essentials Improved

Regular price $100.00
Regular price $100.00 Sale price
SAVE Liquid error (snippets/price line 119): Computation results in '-Infinity'% Sold out

Serving size 1 capsule · 60 servings per container

  • Riboflavin (as Riboflavin 5 Phosphate): 10 mg (769% DV)
  • Vitamin B6 (as Pyridoxal 5 Phosphate): 5 mg (294% DV)
  • Folate (as Calcium Folinate): 17,000 mcg DFE, 10,000 mcg folinic acid (4250% DV)
  • Vitamin B12 (as Adenosylcobalamin, as Hydroxocobalamin): 200 mcg (8333% DV)

Other ingredients: vegetable capsule (cellulose, purified water); may include microcrystalline cellulose (USP) as a filler if necessary. 60 capsules. GMO-, lactose-, soy- and gluten-free.

Take 1 capsule daily, or as directed by your healthcare professional. Best taken with food. Introduce new supplements gradually. Tell your child's doctor about all medications and supplements before starting. Following a weight-based protocol with a practitioner? See the Research Library.

Store in a cool, dry place with the lid tightly closed. Keep out of reach of children. Consult your physician before use if pregnant, nursing, taking medication or with a medical condition.

The date printed on the bottle is the manufacture date, not an expiration date. Speech Essentials is good for 2 years from that date. A bottle manufactured in March 2026, for example, is good through March 2028.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Speech Essentials is a dietary supplement, not a drug, and not a substitute for medical care, medication or therapy.

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Why folinic acid, and why this combination

Research has found that many children with ASD have trouble getting folate into the brain despite normal blood levels, a pattern linked to folate-receptor antibodies (Rossignol & Frye 2021, PMC8622150). Folinic acid can enter by an alternate route that stays open when the main receptor is blocked (Frye 2020, PMC7477301), and in a randomized, placebo-controlled trial children with ASD and language impairment who received it improved on verbal-communication measures, most in the antibody-positive subgroup (Frye 2018, PMC5794882).

Improved adds the cofactors the pathway needs: two active forms of B12, riboflavin-5-phosphate for the MTHFR enzyme, and pyridoxal-5-phosphate for neurotransmitter production.*

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Read the research

We know of no other capsule that combines folinic acid with active B2, active B6 and two forms of B12 in one dose. The high-dose folinic powders on the market are single-ingredient with a few cofactors; children's multivitamins are broad but low-dose; prescription leucovorin is the same folate molecule as a tablet, typically made with lactose.

Speech Essentials is made with folinic acid (calcium folinate), the same folate molecule, 5-formyltetrahydrofolate, that leucovorin is based on and the compound used in the folinic-acid studies in children with ASD (Frye 2018, PMC5794882; Renard 2020). It is a dietary supplement, not a drug: not FDA-approved, not a substitute for any prescribed medication, and we make no claim of pharmaceutical equivalence. Same folate, made without lactose, in a capsule you can open and titrate.