Research Library
Improved vs Pro, ingredient by ingredient
Two look-alike formulas, four real differences in folinic acid, B12, B6 and riboflavin. Who each suits, and why most people should start with Improved.
Improved vs Pro, ingredient by ingredient
Two look-alike formulas, four real differences in folinic acid, B12, B6 and riboflavin. Who each suits, and why most people should start with Improved.
The dairy and folate-receptor connection
Cow's-milk proteins are linked to folate-receptor antibodies. A 2008 study tracked the titers up and down with diet. What that means, done carefully.
The dairy and folate-receptor connection
Cow's-milk proteins are linked to folate-receptor antibodies. A 2008 study tracked the titers up and down with diet. What that means, done carefully.
Why the form of B12 matters (and why not methylcobalamin here)
B12 works alongside folate in the brain, and the form isn't interchangeable. Why our formulas use adenosyl and hydroxocobalamin, not methylcobalamin.
Why the form of B12 matters (and why not methylcobalamin here)
B12 works alongside folate in the brain, and the form isn't interchangeable. Why our formulas use adenosyl and hydroxocobalamin, not methylcobalamin.
Folinic acid vs folic acid vs methylfolate: the folate forms, explained
Folic acid, folinic acid and methylfolate are not interchangeable. Here's the difference, why the form is the whole point, and which one the trials used.
Folinic acid vs folic acid vs methylfolate: the folate forms, explained
Folic acid, folinic acid and methylfolate are not interchangeable. Here's the difference, why the form is the whole point, and which one the trials used.
The retracted trial, and why we stopped citing it
A 2024 folinic acid trial was retracted in January 2026. We removed it from this site. Here's what remains, and how to read small trials honestly.
The retracted trial, and why we stopped citing it
A 2024 folinic acid trial was retracted in January 2026. We removed it from this site. Here's what remains, and how to read small trials honestly.
Leucovorin, folinic acid and the FDA: what the 2025–2026 headlines actually mean
The FDA approved leucovorin in March 2026 only for cerebral folate deficiency with a confirmed FOLR1 variant, not for autism. What that means for parents.
Leucovorin, folinic acid and the FDA: what the 2025–2026 headlines actually mean
The FDA approved leucovorin in March 2026 only for cerebral folate deficiency with a confirmed FOLR1 variant, not for autism. What that means for parents.
A brain that can't take in folate: what the folinic acid studies show, and how we read ...
Plain-language summary of the folinic acid trials in children with autism and speech delay, the folate-receptor antibody research, and how ASDHelp reads the evidence.
A brain that can't take in folate: what the folinic acid studies show, and how we read ...
Plain-language summary of the folinic acid trials in children with autism and speech delay, the folate-receptor antibody research, and how ASDHelp reads the evidence.